Monoclonal Antibodies have been the latest addition to our Therapeutic Armamentum to deal with some complex disease conditions. The M-Ab COCKTAIL ( for early COVID infections ) that was a theme in my recent blog is the latest entrant. Many more will be available, after their successful production in Bio-Labs. M-Abs are cool , revolutionary […]
AMAZING WORLD of MONOCLONAL ANTIBODIES PART ONE Read More »
You must have read the first part of this Blog on MAbs, which gave an idea of the immense therapeutic potential of these Artificial Antibodies. Now let’s explore as to how they are actually manufactured in Bio-Labs. Basic requirements for M-Abs are the following They should be a single clone of Antibodies with specific targeted
AMAZING WORLD of MONOCLONAL ANTIBODIES: PART TWO Read More »
The first two editions of this Blog have dealt with the immense scope of M-Abs as a Novel Therapeutic Modality and HOW they are actually manufactured in Bio-Labs . We will herewith enlist the specific M-Abs and their designated role in specific disorders. The first Monoclonal Antibody was approved by FDA ( Muromonab CD3 ) in 1986
AMAZING WORLD of MONOCLONAL ANTIBODIES. PART THREE Read More »
IMMUNITY has become a key word and concern in Medical Parlance as well as in the Commercial world , with so many urban class people, chatting and seeking Immunity enhancing products – even though this priceless natural treasure has been already gifted to human beings. Scores of Banners and Advertisements are floating around, to befool
IMMUNITY CONUNDRUM simplified Read More »
Cytokine Storm Syndrome is also termed as HYPER-CYTOKINEMIA , meaning a huge excess of CYTOKINES in our body system, which is quite damaging as well as potentially FATAL. CYTOKINE STORM is not exclusive to the COVID PANDEMIC……it can also occur in : Macrophage Activation Syndrome in Rheumatological disorders, like Rheumatoid & Lupus Arthritis. HLH Hemophagocytic Lympho-Histiocytosis. CAR
CYTOKINE STORM SIMPLIFIED Read More »
Finally, a RAY OF HOPE has fallen on the sordid saga of the COVID PANDEMIC LANDSCAPE… Research on Monoclonal Antibodies has come to our rescue. MONOCLONAL ANTIBODY COCKTAIL is made up of two Monoclonal Antibodies. These are actually LAB MANUFACTURED and offer a form of PASSIVE IMMUNITY to newly diagnosed cases of Covid. This Antibody cocktail came into the
NEWER COVID THERAPIES Read More »
Most of our Pediatrician friends would shun TWO TOPICS in our Speciality of Child Care. They are : 1. GENETICS2. IEM = INBORN ERRORS OF METABOLISM. Let’s revisit the essential basics of IEM , because such a situation would be first encountered by one of us, at the periphery. We may not treat such cases,
MEGALOBLASTIC ANEMIA – an emerging GLOBAL PROBLEM and it’s noteworthy ELEVEN – TITBITS 1 Megaloblastic Anemia is better viewed as a multi-system disorder with ANEMIA, centrally featured by large Erythrocytes bigger than 100 fL in terms of MCV ( macro-ovalocytes ) as the classic picture. 2 Nutritional Deficiency of Vitamin B 12 ( COBALMIN) is
NUTRITIONAL ANEMIA Read More »
We, as clinicians, are aware of the CONSTANT DECLINE in the available spectrum of Effective Antibiotics, with the growing menace of Anti-microbial Resistance, creating huge roadblocks in treating serious Nosocomial Infections in ICU settings. However, we are still possessing a limited range of lesser used, but Effective Antibioitics – that can help us BUY TIME
RESERVE ANTIBIOTICS Read More »
Growing ANTIMICROBIAL RESISTANCE to all Antibiotics and all the CHARCHA ( discussion ) around this phenomenon has been the Talk of the Town in the last decade. The frequent Lectures and Orations on this subject often imparted an overwhelming GUILT FEELING in the broader Medico Community, that they have been CARELESS and IRRATIONAL in their
